Research & Education

The Science of Biosynthetic Anti-Aging

Educating medical professionals on the biochemistry behind NAD+ restoration therapy and the clinical evidence supporting injectable NMN and NAD+ supplementation.

What Are NMN and NAD+?

Understanding the two molecules at the core of cellular energy and longevity research.

NMN

β-Nicotinamide Mononucleotide

  • An inherent substance naturally present in the human body
  • Direct biochemical precursor of NAD+
  • Converted to NAD+ via the salvage pathway enzyme NMNAT
  • Found in trace amounts in natural foods such as edamame, broccoli, and avocado
NAD+

Nicotinamide Adenine Dinucleotide

Also known as Coenzyme I

  • Crucial for cellular energy metabolism and ATP production
  • Essential regulator of the immune system
  • Critical for DNA repair mechanisms and genomic stability
  • Activates sirtuins, the family of longevity-associated proteins

The Aging Problem

As we age, NAD+ levels decline dramatically, compromising the cellular processes that keep us healthy.

50%

NAD+ reduces by 50% every 20 years

By age 60, your NAD+ levels may be only 25% of what they were at age 20.

100%50%25%12.5%Age 20Age 40Age 60Age 80

Systems Affected by NAD+ Decline

Brain
Vasculature
Liver
Muscle
Pancreas
Adipose Tissue
Immune System

Why Supplementation Is Necessary

The amount of NMN available through diet is far too low to restore declining NAD+ levels. Targeted supplementation is the only practical solution.

To obtain just 300 mg of NMN from food, you would need:

🫘

16 – 64 kg

Edamame

🥩

72 – 500 kg

Beef

🥑

~19 kg

Avocado

Recommended Daily NMN Dosage by Age

Age 25+

150 mg

Maintenance

Age 40+

300 mg

Restoration

Age 60+

600 mg

Intensive Support

Delivery Methods

Not all routes of administration are equal. Injection offers decisive advantages over oral supplementation.

Oral Supplementation
  • Variable absorption rate (15 – 40%)
  • Degraded by stomach acid and gut enzymes
  • Delayed onset of action
  • Dosage difficult to control precisely
  • Subject to first-pass liver metabolism
Injection — Recommended
  • 100% absorption — full bioavailability
  • Immediate systemic effect
  • High and consistent bioavailability
  • Accurate, clinician-controlled dosage
  • No gastrointestinal degradation

Scientific Validation

Decades of research, Nobel Prize-winning discoveries, and peer-reviewed clinical evidence support NAD+ restoration therapy.

Nobel Prize Foundation

The role of NAD+ in cellular metabolism was first characterised in research that contributed to multiple Nobel Prize awards, underscoring its fundamental importance to human biology.

Published Research

Key findings have been published in the world's most prestigious journals, including Nature, Cell, and Science, confirming the link between NAD+ levels and aging.

Clinical Results

85%

Sleep Improvement

of participants reported improved sleep quality with NMN injection therapy

80%

Energy Improvement

of participants reported increased energy levels with NAD+ injection therapy

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For professional medical use only. Not for retail sale.